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Antioxidant agent-5

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    10
    TargetMol | Inhibitors_Agonists
  • Natural Products
    6
    TargetMol | Natural_Products
Antioxidant agent-5
T621112684291-60-7
Antioxidant agent-5 (compound D-6) is a potent antioxidant that inhibits oxLDL-induced increases in ROS levels and NF-κB nuclear translocation. It also prevents oxLDL (oxidized LDL)-induced apoptosis (VECs), activates the Nrf2 HO-1 antioxidant pathway, and exhibits protective activity against oxLDL-induced endothelial damage.
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6-8 weeks
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Octyl gallate
Gallic acid octyl ester, n-Octylgallate, Octyl 3,4,5-trihydroxybenzoate, Progallin O, Stabilizer GA-8
T2S18651034-01-1
1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, with a minimum inhibitory concentration (MIC) value of 125 ug mL. 4. Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.5. Octyl Gallate is a potential anticancer agent, it exhibited decreased MCF-7 & MDA-MB-231 survival and induced apoptosis, with IC50 value of 40 uM. 6. Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) has antiviral activity, it shows an inhibitory effect on the growth of herpes simplex virus type 1 (HSV-1) in HEp-2 or Vero cells. 7. Octyl gallate shows antifungal activity against Saccharomyces cerevisiae ATCC7754 and Zygosaccharomyces bailii ATCC 60483.
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Pentagalloylglucose
Penta-O-galloyl-β-D-glucose, 1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose, 1,2,3,4,6-O-Pentagalloylglucose
T379414937-32-7
1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses potent anti-proliferative and anti-invasive effects, it also has inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity. 3. PGG may serve as a model for the development of new types of anti-diabetic and anti-metabolic syndrome therapeutics. 4. 1, 2, 3, 4, 6-Penta- O -galloyl-β- d -glucose has vasodilatory and anti-inflammatory effects, it dilates vascular smooth muscle and suppresses the vascular inflammatory process via endothelium-dependent nitric oxide (NO) cGMP signaling. 5. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose can decrease the level of extracellular hepatitis B virus (HBV) (IC5, 1. microg ml) in a dose-dependent manner, it also can reduce the HBsAg level by 25% at a concentration of 4 microg ml; the gallate structure of PGG may play a critical role in the inhibition of anti-HBV activity, suggests that PGG could be a candidate for developing an anti-HBV agent. 6. 1, 2, 3, 4, 6-Penta-O-galloyl-β-D-glucose has anti-parasitic activity, displays an EC5 value of 67 μM, at least 6.6-fold more effective than the standard drug benznidazole against trypomastigote forms of T. cruzi.
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Fulvene-5
T113331075723-01-1
Fulvene-5 is a chemical compound that exhibits antitumor activity. It functions as a potent inhibitor of NADPH oxidase 4 (NOX4) and possesses antioxidant properties. Additionally, Fulvene-5 acts as a reactive oxygen species (ROS) modifying agent and a powerful radioprotector.
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6-8 weeks
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Neuroprotective agent 5
T200770
Neuroprotective agent 5 (compound 28) acts as a brain-penetrating agent with anti-neuroinflammatory, antioxidant, and neuroprotective properties. It exhibits potent inhibition of nitric oxide (NO) with an EC50 of 0.49 μM and suppresses the release of pro-inflammatory mediators PGE2 and TNF-α. Additionally, it downregulates the expression of iNOS and COX-2 proteins, facilitating the polarization of BV-2 cells from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype. Neuroprotective agent 5 also dose-dependently inhibits acetylcholinesterase (AChE) activity and the aggregation of Aβ42. This compound is useful for research into Alzheimer's disease.
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Obtusifolin
T4S0969477-85-0
1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be a novel anti-breast-cancer bone me
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8-Gingerol
T6S168423513-08-8
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristics. 5. 8-Gingerol seems to be effect
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TargetMol | Inhibitor Sale
Antioxidant agent-18
T83026143016-73-3
Antioxidant Agent-18 (Compound 5), a flavonol glycoside derived from Ginkgo biloba, exhibits antioxidant properties through its ability to scavenge DPPH radicals (IC50: 15.8 μM) and reduce cytochrome c (IC50: 14.7 μM).
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Antioxidant/anticancer agent 1
T856981449470-38-5
Antioxidant anticancer agent 1 (compound 5) is a Schiff base derivative of pyrimidine and pyrimidine hydroxy-1-naphthaldehyde, exhibiting antibacterial, antioxidant, antifungal, and anticancer properties [1].
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10-14 weeks
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6-Acetonyldihydrochelerythrine
TN315222864-92-2
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg mL and 14.6, respectively. 6-Acetonyldihydrochelerythrine is
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